The harmful use of alcohol worldwide accounted for an estimated 3 million deaths in 2016.1 The main alcohol-attributed causes of death include liver cirrhosis, cardiovascular disease (CVD), some cancers (eg, mouth and throat, oesophagus, and liver), tuberculosis, pneumonia, alcohol use disorders, and injuries
Higher alcohol intake increased the risks of death overall and from major diseases for men in China. There was no genetic evidence of protection from moderate drinking for all-cause and cause-specific mortality.